BMAL1 (Acetyl Lys538) Polyclonal Antibody

Name: BMAL1 (Acetyl Lys538) Polyclonal Antibody
SKU: POLY-AP00913
Availability: InStock

Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB, ELISA, TR-FLISA, TR-FRET
Storage: -20°C for 1 year
Conjugation with Bright-Dtech™ on request

Size

Clear

SKU: POLY-AP00913 Category: Antibodies Tag: Primary Antibody

Description
Additional information

Description

Data sheet BMAL1 Polyoclonal Antibody

Background: The protein encoded by ARNTL is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in ARNTL have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for ARNTL.

Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular weight: 68762

Gene ID: Human: 406; Mouse: 11865; Rat: 29657

Synonyms: ARNTL; BHLHE5; BMAL1; MOP3; PASD3; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3Brain and muscle ARNT-like 1; Class E basic helix-loop-helix pr

Research area:Cardiovascular

Target protein: ARNTL