Cleaved PARP Monoclonal Antibody (Mix)

Name: Cleaved PARP Monoclonal Antibody (Mix)
SKU: POLY-MCA0024
Availability: InStock

Clonality: Monoclonal
Host: Mouse
Reactivity: Human
Application: IF, ICC, WB, IHC-p
Storage: -20°C for 1 year
Conjugation with Bright-Dtech™ on request

Size

Clear

SKU: POLY-MCA0024 Category: Antibodies Tag: Primary Antibody

Description
Additional information

Description

Data sheet Cleaved PARP Monoclonal Antibody (Mix)

Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Purification: Affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml

Formulation: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Molecular weight: N/A

Gene ID: Human: 14225591

Synonyms:PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

Research area: Epigenetics and nuclear signaling; Metabolism; Cancer; Cell biology

Target protein: PARP1