CK8 Monoclonal Antibody (8G8)

Description

Data sheet CK8 Monoclonal Antibody (8G8)

 

Background:This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Purification:Affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml

Formulation: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Molecular weight:53573

Gene ID: Human: 3856; Mouse: 16691; Rat: 25626

Synonyms:KRT8; CYK8; Keratin; type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8

Research area:Signal transduction; Cancer

Target protein: KRT8