CD4 Monoclonal Antibody (11A1)

Description

Data sheet CD4 Monoclonal Antibody (11A1)

 

Background: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Purification:Affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml

Formulation: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Molecular weight: 51111

Gene ID: Human: 920; Mouse: 12504; Rat: 24932

Synonyms:CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4; Leu-3; CD4

Research area:Immunology; Stem cells

Target protein: CD4