CD133 Polyclonal Antibody

Description

Data sheet CD133 Polyclonal Antibody

 

Background:PROM1 encodes a pentaspan transmembrane glycoprotein. Prominin-1 localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular weight:97202

Gene ID: Human: 8842

Synonyms:PROM1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD133

Research area:Neuroscience

Target protein: PROM1