Catalase Polyclonal Antibody

Description

Data sheet Catalase Polyclonal Antibody

 

Background: CAT (catalase) encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer’s disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in CAT have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by CAT.

Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular weight: 59756

Gene ID: Human: 847; Mouse: 12359; Rat: 24248

Synonyms: CAT; Catalase

Research area: Tags & Cell Markers

Target protein: CAT