Advancing diagnostic technologies with high-performance solutions
Poly-Dtech is your trusted partner in diagnostic innovation, specializing in high-performance fluorescent nanoparticles and advanced immunoassays, including LFIA, TR-FRET, FLISA, and multiplexing solutions. From concept to final product, we ensure superior sensitivity, specificity, and ease of use.
We work closely with partners to develop tailored diagnostic solutions, offering custom assay development, OEM solutions, technology licensing, and specialized training. At Poly-Dtech, we understand that every application is unique. That’s why our technologies are designed to be highly adaptable, serving a wide range of fields, including life sciences, clinical diagnostics, veterinary health, industrial testing, and food safety.
Our proprietary ultra-fluorescent lanthanide nanoparticles (Bright-Dtech™) enable unparalleled assay performance, delivering rapid and quantitative results comparable to laboratory-based methods.With a commitment to innovation, precision, and seamless integration, we help our partners push the boundaries of diagnostic testing. Whether you are developing a new assay or looking to enhance an existing platform, Poly-Dtech is your trusted partner for next-generation fluorescence-based diagnostics.
Poly-Dtech: Your partner in fluorescence-based assay development
Lateral flow immunoassays (LFIA)
Traditional lateral flow immunoassays (LFIA) are valued for their simplicity and speed but often lack sensitivity and quantification. Poly-Dtech solves this with Bright-Dtech™, our ultra-fluorescent lanthanide nanoparticles, offering superior sensitivity and specificity over gold nanoparticles. This innovation enables lab-grade, quantitative results comparable to ELISA and Cobas/Siemens systems, all within minutes—even in the field.
We help partners integrate these advanced nanoparticles into their LFIA, enhancing detection or converting existing assays into a lateral flow format for superior performance.
Why choose Bright-Dtech™ for lateral flow assays?
- Achieve laboratory-level performance in the field: Bright-Dtech™ combines the speed of lateral flow with the precision of high-end laboratory analyzers, ensuring reliable and sensitive biomarker detection.
- Up to 100x higher sensitivity vs traditional rapid tests: Leveraging our lanthanide-based fluorescent nanoparticles, Bright-Dtech™ significantly improves detection limits, making it ideal for low-concentration biomarker detection.
- Quantitative & reproducible results: Unlike traditional colorimetric tests, Bright-Dtech™ enables precise, quantitative readouts, allowing for better clinical decision-making.
- Fast turnaround – results in 10-15 minutes: Rapid diagnostic results with a time-resolved fluorescence reader, ensuring a seamless transition from lab to field applications.
How we support your LFIA development ?
- Custom LFIA development: We work with partners to design and optimize fluorescence-based LFIA tests with superior sensitivity and quantification. By integrating our Bright-Dtech™ ultra-fluorescent lanthanide nanoparticles, we enhance assay performance through optimized nanoparticle selection, conjugation, membrane compatibility, and reagent formulation. Our solutions scale seamlessly from feasibility to full production, ensuring a smooth transition to fluorescence-based detection.
- Nanoparticle conjugation: With expertise in nanoparticle functionalization, we offer custom conjugation services, coupling proteins, antibodies, or oligonucleotides with our ultra-fluorescent nanoparticles. We provide ready-to-use conjugates, reducing development time and ensuring reproducibility.
- Link-Dtech technology: For labs and manufacturers looking to create their own nanoparticle conjugates, Link-Dtech™ is a ready-to-use kit for easy antibody or ligand coupling. This allows full control over assay development with high-performance fluorescent nanoparticles. Watch the YouTube video to learn more about the protocol.
- Licensing, OEM, and training: We offer flexible licensing, OEM solutions, and training programs for partners integrating Bright-Dtech™technology. Whether scaling production, ensuring regulatory compliance, or transferring technology, our team provides full support.
Lateral flow reader integration: To fully exploit the power of fluorescence-based LFIA, an adapted reader is essential. While we are currently developing a dedicated reader solution, we are also open to collaborating with manufacturers to co-develop custom fluorescence readers that further enhance sensitivity, quantification, and ease of use for your assays.
By partnering with Poly-Dtech, you gain access to a turnkey solution for transforming your LFIA into high-performance diagnostic tools, setting new standards in sensitivity and reliability.
Possible applications of our lateral flow solutions
- Diagnostics: Rapid biomarker detection for infectious diseases, cardiac conditions, emergency care, point-of-care testing (POCT), patient monitoring, and chronic diseases.
- Veterinary Health: Reliable tests for animal health monitoring and disease surveillance.
- Food Safety & Environmental Testing: Detection of pathogens and contaminants to ensure regulatory compliance.
Discover how our Bright-Dtech™ lanthanide nanoparticles enhance sensitivity and quantification in lateral flow assays. Watch the video to see real-time results
Fluorescence-based microplate immunoassays
(TR-FRET – Multiplexing – FLISA)
Poly-Dtech’s proprietary fluorescence technology extends beyond lateral flow to high-performance immunoassays, enabling enhanced biomarker detection through techniques like TR-FRET, FLISA, and Multiplexing. Our advanced ultra-fluorescent lanthanide nanoparticles (Bright-Dtech™) offer unmatched sensitivity and flexibility, allowing researchers, developers and manufacturer to achieve rapid, reliable, and highly quantitative results with minimal background interference.
Why choose Poly-Dtech and its technology?
We understand that assay development is not a one-size-fits-all process. Whether you need a fully customized immunoassay, a specific target of interest, the conversion of your ELISA assays into TR-FRET or multiplexing, or the optimization of an existing platform, our team of experts provides end-to-end support—from feasibility studies to full-scale production. Our goal is to help you achieve superior assay performance while reducing development time and costs.
Advantages of our fluorescence-based immunoassays
- Simple and cost-effective use – Requires little to no washing steps and only a low sample volume.
- Accelerated analysis time – Up to 4× faster than conventional methods.
- Reduced costs – Optimized solutions minimize reagent and sample consumption, as well as processing time.
- Seamless integration – Fully compatible with standard plate readers and existing laboratory workflows.
- Superior sensitivity – Limit of Detection (LOD) improved by 10× to 100×, depending on the biological context.
- Robust and reliable results – Ultra-stable fluorescence signals ensure consistent performance across multiple applications.
Tailored immunoassay development to meet your specific needs
At Poly-Dtech, we specialize in developing custom fluorescence-based immunoassays that are precisely adapted to your targets, applications, and workflow requirements. Whether you need to enhance an existing assay or develop a completely new solution, our expertise in TR-FRET, FLISA, and multiplexing enables us to create high-performance immunoassays tailored to your needs. We help you chieve susperior performance through:
- Assay customization for specific targets: We develop high-sensitivity immunoassays optimized for your specific biomarkers, ensuring maximum signal intensity, minimal background noise, and robust reproducibility.
- Conversion & optimization of existing assays: Looking to upgrade your ELISA, lateral flow, or other assays to a fluorescence-based format (TR-FRET, FLISA, or multiplexing)? We seamlessly adapt your existing protocols to enhance sensitivity, reduce processing time, and simplify workflows.
- Multiplexing solutions without complex instrumentation: We design custom multiplexed assays to detect multiple biomarkers in a single test, reducing sample volume requirements and increasing data output—all without the need for costly specialized equipment.
- Seamless integration & compatibility: Our assays are developed to be fully compatible with standard laboratory instrumentation, ensuring an easy transition into your existing workflow.
Whether you need a custom TR-FRET assay, an optimized FLISA for high-throughput screening, or a multiplexed detection platform, Poly-Dtech provides end-to-end expertise to accelerate your development and deliver superior assay performance.
Possible applications of our fluorescence immunoassays
- Oncology & chronic disease biomarker detection – Early detection and monitoring of cancer, cardiovascular diseases, and neurodegenerative disorders.
- Pharmaceutical & drug discovery – High-throughput screening, lead optimization, and pharmacokinetic analysis.
- Clinical research & diagnostics – Precision medicine, personalized diagnostics, and clinical biomarker validation.
- Biotech & life sciences – Advanced research applications, including protein interactions and immune response profiling.
- Food safety & industrial testing – Rapid detection of contaminants, toxins, and pathogens in food and environmental samples.
Other Fluorescent Applications
Beyond immunoassays, Poly-Dtech’s ultra-fluorescent lanthanide nanoparticles open exciting possibilities for a wide range of life science applications. Their exceptional sensitivity, stability, and compatibility with existing laboratory workflows make them a promising tool for enhancing detection and quantification across various research and diagnostic techniques.
Potential applications of our nanoparticles in life sciences
- Western Blot – Could enhance signal detection for improved protein quantification.
- Flow Cytometry – May increase fluorescence intensity for more precise single-cell analysis.
- PCR & qPCR – Potential use as fluorescent probes for highly sensitive real-time amplification monitoring.
- Microscopy & Imaging – Offers high-contrast fluorescent markers that could improve cellular and molecular visualization.
- Biosensors & Microarrays – Could optimize multi-analyte detection in high-throughput research applications.
While our core expertise lies in immunoassays, we are eager to explore new applications and collaborate with researchers and developers looking to push the boundaries of fluorescence-based detection. If you’re working on innovative ways to integrate ultra-fluorescent nanoparticles, let’s discuss how our technology could fit into your workflow.
Partner with Poly-Dtech
Leverage our expertise in lateral flow immunoassays and ultra-fluorescent technologies to enhance your diagnostic capabilities. Whether you require ready-to-use solutions or a trusted partner for custom assay development, Poly-Dtech is here to innovate with you.
Contact us today to discuss how we can support your diagnostic and research needs.